Jasmine H Francis
Memorial Sloan Kettering Cancer Center
USA
Title: Classification and treatment of vitreous seeds in retinoblastoma using intra-arterial and intra-vitreal techniques
Biography
Biography: Jasmine H Francis
Abstract
Up until a decade ago, there was inadequate treatment for vitroeus seeds in retinobalstoma and most of these eyes came to enucleation. However, with the increased use of both intra-arterial and intra-vitreal chemotherapy, the ocular survival rate for these eye is now greater than 95%. As we salvage more of these eyes, our understanding of vitreous seeds has also improved greatly. Our group has previously proposed a classification system for vitreous seeds, which predicts response to and drug requirements for intra-vitreal melphalan. Furthermore, there are particular tumor, eye and patient characteristics that also correspond with the vitreous seeds classification. We, our recent advancements over the past decade and particularly the last two years, not only has our treatment of vitreous seeds in retinoblastoma greatly improved, but so has our understanding of this disease entity.
