Caroline Mvilongo Tsimi has completed her MD degree from Yaounde Faculty of Medicine and Biomedical Sciences. She is an Ophthalmologist at Yaounde Central Hospital and has published some papers in reputed journals.
Introduction: Retinoblastoma is an embryonal tumor of neuroectodermal origin, highly malignant affecting the young child and the infant. It is bilateral in 40% of cases. We report 2 clinical cases of bilateral retinoblastoma with extra-retinal diffusion which is a poor prognosis factor. Case 1: DW, 20 months brought in our ophthalmology service in 2009 with a tumor of the left eye since one month with a past history of leucocoria since birth. At the ophthalmology exam, he was classified at stage V of Reese- Ellsworth for the contro-lateral right eye and orbital extension of the left eye. He has been enucleated for the left eye and received 3 doses of chemotherapy. The patient was lost of view 2 months after the surgery. Case 2: H O, 3 years central African refugee referred in our ophthalmology service on June 2015 for the care of a tumor of the right eye since 3 months. She had a leucocoria in the right eye since one year; with past history of 1st degree consanguinity. The ophthalmology exam showed a great tumor with necrosis and inflammation of the right eye. At the left eye, sub-retinal mass with retinal detachment stage-V of Reese- Ellsworth, she has received neoadjuvant chemotherapy and exenteration of the right eye. She died few hours after the surgery. These 2 cases have been seen late in an appropriate ophthalmology unit. The prognosis was poor because of the extra retinal diffusion of the tumor.
Seong-Joon Kim has completed his PhD from Seoul National University. He is a Professor in Department of Ophthalmology, Seoul National University College of Medicine with specialization in Strabismology and Neuro-Ophthalmology. He has published more than 80 papers in reputed journals and has been serving as an Editorial Board Member of Korean Journal of Ophthalmology.
Amblyopia is the most common cause of visual impairment in children and most of current treatments are monocular patching or penalization. Recent studies report that abnormal binocular interactions play a key role in amblyopia. The mechanism of dichoptic presentation is presenting the strong stimulus to the amblyopic eye and another weak stimulus to the normal fellow eye. The device which directly targets the binocular function using dichoptic presentation is developed. The developed device and software program separate the 3D images and control the visual inputs into the both eyes using head-mounted display. It increases the contrast, size and intensity of the 3D target to the amblyopic eye and decreases those to the normal fellow eye. This separation of 3D images is expected to improve the monocular visual acuity of the amblyopic eye with the reduction of suppression and strengthen the binocular fusion including stereopsis. The newly developed binocular therapy using head-mounted display is hand-held and convenient. Further investigation is needed to prove the effectiveness in improvement of both monocular and binocular vision in children and adults with amblyopia.